A4D1B5 | GSAP_HUMAN | Gamma-secretase-activating protein (GSAP)
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3703681 | IC50 | = | 1.0 | nM | 535.06 | O=C(COc1ccc(F)cc1)Nc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccc(Cl)s1 | Homo sapiens | CHEMBL3705978 | single protein format | |
| CHEMBL3703680 | IC50 | = | 1.2 | nM | 490.51 | CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O | Homo sapiens | CHEMBL3705978 | single protein format |