O00429 | DNM1L_HUMAN | Dynamin-1-like protein (DNM1L)
3D structures mapped by conservation among orthologs
[ Domain: "P-loop containing nucleoside triphosphate hydrolases" // Dynamin_N ]
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[ Domain: "Middle and GTPase effector domains in dynamin-related proteins" // Dynamin_M ]
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[ Domain: pdbs with more than 2 multi-domains ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4471636 | IC50 | = | 720.0 | nM | 500.62 | Cc1cc(C(=O)Nc2ccc(-c3ccc(C(=O)O)cc3)cc2)n(Cc2csc(N3CCCCC3)n2)c1 | Homo sapiens | CHEMBL4418475 | single protein format | |
| CHEMBL4467972 | IC50 | = | 910.0 | nM | 448.56 | Cc1cc(C(=O)Nc2ccc(-c3nn[nH]n3)cc2)n(Cc2csc(N3CCCCC3)n2)c1 | Homo sapiens | CHEMBL4418475 | single protein format |