O14786 | NRP1_HUMAN | Neuropilin-1 (NRP1)
3D structures mapped by conservation among orthologs
[ Domain: "Concanavalin A-like lectins/glucanases" // MAM ]
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[ Domain: "Galactose-binding domain-like" // F5_F8_type_C ]
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[ Domain: "Spermadhesin, CUB domain" // CUB ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4217624 | IC50 | = | 609.0 | nM | 586.7 | N=C(N)NCCC[C@H](NC(=O)c1sccc1NS(=O)(=O)c1cc(-c2ccc(CN)cc2)cc2c1OCC2)C(=O)O | Homo sapiens | CHEMBL4183435 | cell-based format | |
| CHEMBL4279036 | IC50 | = | 800.0 | nM | 541.66 | N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)C(CCN)NC(=O)C(N)CCCCN=C(N)N)C(=O)O | Homo sapiens | CHEMBL4268072 | single protein format |