O14936 | CSKP_HUMAN | Peripheral plasma membrane protein CASK (CASK)
3D structures mapped by conservation among orthologs
[ Domain: "P-loop containing nucleoside triphosphate hydrolases" // Guanylate_kin ]
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[ Domain: "Protein kinase" // Pkinase_Tyr ]
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[ Domain: "L27 domain" // L27_like ]
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[ Domain: "PDZ domain" // PDZ ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2312304 | Ki | = | 15.0 | nM | 507.42 | O=C(NCCCN1CCOC1=O)c1cnc(NCc2cc(Cl)ccc2Cl)nc1NC1CCCC1 | Homo sapiens | CHEMBL4831227 | cell-based format | |
| CHEMBL2312304 | IC50 | = | 130.0 | nM | 507.42 | O=C(NCCCN1CCOC1=O)c1cnc(NCc2cc(Cl)ccc2Cl)nc1NC1CCCC1 | Homo sapiens | CHEMBL4831227 | cell-based format |