O15527 | OGG1_HUMAN | N-glycosylase/DNA lyase (OGG1)
3D structures mapped by conservation among orthologs
[ Domain: "DNA-glycosylase" // HhH-GPD ]
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[ Domain: "TATA-box binding protein-like" // OGG_N ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4441163 | IC50 | = | 220.0 | nM | 261.13 | NNC(=O)c1sc2cccc(Cl)c2c1Cl | Homo sapiens | CHEMBL4422181 | single protein format | |
| CHEMBL4470975 | IC50 | = | 270.0 | nM | 320.85 | CC1CCCC/C1=N/NC(=O)c1sc2ccccc2c1Cl | Homo sapiens | CHEMBL4422181 | single protein format | |
| CHEMBL4436904 | IC50 | = | 300.0 | nM | 226.69 | NNC(=O)c1sc2ccccc2c1Cl | Homo sapiens | CHEMBL4422180 | single protein format | |
| CHEMBL4437745 | IC50 | = | 330.0 | nM | 332.79 | O=C(N/N=C/c1ccc(F)cc1)c1sc2ccccc2c1Cl | Homo sapiens | CHEMBL4422181 | single protein format | |
| CHEMBL4568814 | IC50 | = | 340.0 | nM | 282.34 | O=C(NN=C1CCCCC1)c1cc2ccccc2cc1O | Homo sapiens | CHEMBL4422181 | single protein format | |
| CHEMBL124433 | IC50 | = | 390.0 | nM | 215.05 | NNC(=O)c1ccc(Br)cc1 | Homo sapiens | CHEMBL4422180 | single protein format | |
| CHEMBL4564367 | IC50 | = | 630.0 | nM | 295.18 | O=C(NN=C1CCCCC1)c1ccc(Br)cc1 | Homo sapiens | CHEMBL4422181 | single protein format |