O15550 | KDM6A_HUMAN | Lysine-specific demethylase 6A (KDM6A)
3D structures mapped by conservation among orthologs
[ Domain: "Double-stranded beta-helix" // JmjC_1 ]
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[ Domain: "LIM domain-like" // KOG1246_3rd ]
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[ Domain: "C-terminal helical domain in Jumonji domain-containing histone demethylases" // KOG1246_2nd ]
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[ Domain: pdbs with more than 2 multi-domains ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3787193 | IC50 | < | 100.0 | nM | 322.41 | CCN(CCN(C)C)C(=O)CNCc1cc(C(=O)OC)ccn1 | Homo sapiens | CHEMBL3789214 | assay format | |
| CHEMBL3786593 | IC50 | < | 100.0 | nM | 336.44 | CCOC(=O)c1ccnc(CNCC(=O)N(CC)CCN(C)C)c1 | Homo sapiens | CHEMBL3789214 | assay format |