O95363 | SYFM_HUMAN | "Phenylalanine--tRNA ligase, mitochondrial" (FARS2)
3D structures mapped by conservation among orthologs
[ Domain: "Anticodon-binding domain of PheRS" // FDX-ACB ]
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[ Domain: "Class II aaRS and biotin synthetases" // tRNA-synt_2d ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL281860 | IC50 | = | 170.0 | nM | 496.35 | O=C1O[C@H]2c3ccccc3[C@H](O)[C@]23O[C@@H](c2ccccc2)[C@H](C(=O)Nc2ccc(Cl)c(Cl)c2)[C@H]13 | Homo sapiens | CHEMBL768844 | single protein format | |
| CHEMBL284654 | IC50 | = | 470.0 | nM | 496.35 | O=C1O[C@H]2c3ccccc3[C@@H](O)[C@]23O[C@@H](c2ccccc2)[C@H](C(=O)Nc2ccc(Cl)c(Cl)c2)[C@H]13 | Homo sapiens | CHEMBL768844 | single protein format |