P0DMV8 | HS71A_HUMAN | Heat shock 70 kDa protein 1A (HSPA1A)

3D structures mapped by conservation among orthologs

[ Domain: "Ribonuclease H-like" // HSP70_1st ]

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[ Domain: "Ribonuclease H-like" // MreB_Mbl_C ]

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[ Domain: "Heat shock protein 70kD (HSP70), peptide-binding domain" // HSP70_2nd ]

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[ Domain: "Heat shock protein 70kD (HSP70), C-terminal subdomain" // HSP70_3rd ]

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[ Domain: pdbs with more than 2 multi-domains ]

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[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

IC50 table

molecule_chembl_id	structure	assay_type	relation	values	units	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL502775		IC50	=	332.0	nM	314.25	O=C(O)/C=C/c1c2ccc(=O)c(O)c-2oc2c(O)c(O)ccc12	Homo sapiens	CHEMBL1614297	single protein format
CHEMBL1481974		IC50	=	578.0	nM	316.27	O=C(O)CCc1c2ccc(=O)c(O)c-2oc2c(O)c(O)ccc12	Homo sapiens	CHEMBL1614297	single protein format
CHEMBL471004		IC50	=	634.0	nM	394.38	CC1C2C=CC1C(c1c3ccc(=O)c(O)c-3oc3c(O)c(O)ccc13)C2C(=O)O	Homo sapiens	CHEMBL1614297	single protein format
CHEMBL6246		IC50	=	760.0	nM	302.19	O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23	Homo sapiens	CHEMBL1614054	single protein format