P10599 | THIO_HUMAN | Thioredoxin (TXN)
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2315295 | IC50 | = | 90.0 | nM | 309.42 | O=[N+]([O-])c1ccc2nc(SSC3CCCCC3)[nH]c2c1 | Homo sapiens | CHEMBL2319792 | cell-based format | |
| CHEMBL2315297 | IC50 | = | 170.0 | nM | 316.85 | Fc1cc2nc(SSC3CCCCC3)[nH]c2cc1Cl | Homo sapiens | CHEMBL2319792 | cell-based format | |
| CHEMBL2315294 | IC50 | = | 240.0 | nM | 368.53 | O=C(c1ccccc1)c1ccc2nc(SSC3CCCCC3)[nH]c2c1 | Homo sapiens | CHEMBL2319792 | cell-based format | |
| CHEMBL2315292 | IC50 | = | 290.0 | nM | 297.41 | Nc1nc(O)c2[nH]c(SSC3CCCCC3)nc2n1 | Homo sapiens | CHEMBL2319792 | cell-based format | |
| CHEMBL2315306 | IC50 | = | 340.0 | nM | 210.33 | CCSSc1nc2ccccc2[nH]1 | Homo sapiens | CHEMBL2319792 | cell-based format | |
| CHEMBL2315290 | IC50 | = | 450.0 | nM | 290.46 | c1ccc(-c2cnc(SSC3CCCCC3)[nH]2)cc1 | Homo sapiens | CHEMBL2319792 | cell-based format | |
| CHEMBL2315299 | IC50 | = | 510.0 | nM | 281.47 | c1ccc2sc(SSC3CCCCC3)nc2c1 | Homo sapiens | CHEMBL2319792 | cell-based format | |
| CHEMBL2315288 | IC50 | = | 540.0 | nM | 306.46 | Nn1c(SSC2CCCCC2)nnc1-c1ccccc1 | Homo sapiens | CHEMBL2319792 | cell-based format |