P11172 | UMPS_HUMAN | Uridine 5'-monophosphate synthase (UMPS)
3D structures mapped by conservation among orthologs
[ Domain: "TIM barrels" // OMPdecase ]
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[ Domain: "PRTase-like" // Pribosyltran ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1164953 | Ki | = | 17.0 | nM | 339.2 | NC(=O)c1[nH]nc([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c1O | Homo sapiens | CHEMBL1168988 | single protein format | |
| CHEMBL2105330 | Ki | = | 17.0 | nM | 259.22 | NC(=O)c1[nH]nc([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O | Homo sapiens | CHEMBL4220277 | single protein format | |
| CHEMBL473587 | Ki | = | 350.0 | nM | 370.23 | CCc1c(F)c(=O)[nH]c(=O)n1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL1022248 | single protein format |