molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL1770735 | Ki | = | 10.0 | nM | 163.24 | NCc1cc2ccccc2s1 | Homo sapiens | CHEMBL3390302 | single protein format | |
CHEMBL3640770 |
|
IC50 | = | 20.0 | nM | 177.25 | CCC1CCC(c2cccnc2)O1 | Homo sapiens | CHEMBL3705713 | single protein format |
CHEMBL359657 |
|
Ki | = | 20.0 | nM | 190.27 | NCc1ccc(-c2cccnc2)s1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL180270 |
|
Ki | = | 40.0 | nM | 160.22 | CN(C)CC#Cc1cccnc1 | Homo sapiens | CHEMBL4422408 | microsome format |
CHEMBL178090 |
|
Ki | = | 40.0 | nM | 174.2 | NCc1ccc(-c2cccnc2)o1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3358193 |
|
Ki | = | 60.0 | nM | 163.2 | O=Cc1cc2ccncc2s1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358223 |
|
Ki | = | 70.0 | nM | 145.16 | O=Cc1ccc2[nH]ccc2c1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358215 |
|
Ki | = | 70.0 | nM | 146.14 | O=Cc1ccc2occc2c1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358192 |
|
Ki | = | 70.0 | nM | 163.2 | O=Cc1cc2cnccc2s1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL360541 |
|
Ki | = | 90.0 | nM | 132.17 | NCC#Cc1cccnc1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3358194 |
|
Ki | = | 90.0 | nM | 197.69 | NCc1csc2ccc(Cl)cc12 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL179669 |
|
Ki | = | 100.0 | nM | 175.26 | Cc1ccsc1-c1cccnc1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL1770735 |
|
IC50 | = | 100.0 | nM | 163.24 | NCc1cc2ccccc2s1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL359657 |
|
IC50 | = | 160.0 | nM | 190.27 | NCc1ccc(-c2cccnc2)s1 | Homo sapiens | CHEMBL3706122 | assay format |
CHEMBL441367 |
|
IC50 | = | 160.0 | nM | 192.65 | Clc1ccc(Cn2ccnc2)cc1 | Homo sapiens | CHEMBL3706122 | assay format |
CHEMBL3640760 |
|
Ki | = | 170.0 | nM | 175.26 | Cc1cncc(-c2ccsc2)c1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL369285 |
|
Ki | = | 180.0 | nM | 204.3 | CNCc1ccc(-c2cccnc2)s1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3358216 |
|
Ki | = | 200.0 | nM | 143.14 | N#Cc1ccc2occc2c1 | Homo sapiens | CHEMBL3390307 | single protein format |
CHEMBL178090 |
|
IC50 | = | 200.0 | nM | 174.2 | NCc1ccc(-c2cccnc2)o1 | Homo sapiens | CHEMBL3706122 | assay format |
CHEMBL179669 |
|
IC50 | = | 200.0 | nM | 175.26 | Cc1ccsc1-c1cccnc1 | Homo sapiens | CHEMBL3706122 | assay format |
CHEMBL179621 |
|
Ki | = | 210.0 | nM | 193.25 | Cc1ccsc1-c1ccc(F)nc1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL361153 |
|
Ki | = | 220.0 | nM | 161.23 | c1cncc(-c2ccsc2)c1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL178780 |
|
Ki | = | 230.0 | nM | 235.29 | c1ccc(Cn2cnc(-c3cccnc3)c2)cc1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL178534 |
|
Ki | = | 240.0 | nM | 204.25 | O/N=C/c1ccc(-c2cccnc2)s1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL178516 |
|
Ki | = | 250.0 | nM | 145.16 | c1cncc(-c2c[nH]cn2)c1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL368883 |
|
Ki | = | 250.0 | nM | 159.19 | Cc1nccn1-c1cccnc1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL178938 |
|
Ki | = | 280.0 | nM | 188.23 | CNCc1ccc(-c2cccnc2)o1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3358192 |
|
IC50 | = | 300.0 | nM | 163.2 | O=Cc1cc2cnccc2s1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3640764 |
|
IC50 | = | 330.0 | nM | 178.24 | NCC1CCC(c2cccnc2)O1 | Homo sapiens | CHEMBL3705713 | single protein format |
CHEMBL4443442 |
|
IC50 | = | 330.0 | nM | 178.24 | NC[C@@H]1CC[C@@H](c2cccnc2)O1 | Homo sapiens | CHEMBL4422404 | microsome format |
CHEMBL179477 |
|
IC50 | = | 360.0 | nM | 145.16 | c1cncc(-n2ccnc2)c1 | Homo sapiens | CHEMBL3705713 | single protein format |
CHEMBL178781 |
|
IC50 | = | 360.0 | nM | 159.19 | Cc1cn(-c2cccnc2)cn1 | Homo sapiens | CHEMBL4422404 | microsome format |
CHEMBL3640765 |
|
IC50 | = | 360.0 | nM | 242.12 | BrCC1CCC(c2cccnc2)O1 | Homo sapiens | CHEMBL3705713 | single protein format |
CHEMBL3358207 |
|
IC50 | = | 400.0 | nM | 163.2 | O=Cc1cc2cccnc2s1 | Homo sapiens | CHEMBL3390303 | single protein format |
CHEMBL3358223 |
|
IC50 | = | 400.0 | nM | 145.16 | O=Cc1ccc2[nH]ccc2c1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358193 |
|
IC50 | = | 400.0 | nM | 163.2 | O=Cc1cc2ccncc2s1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358194 |
|
IC50 | = | 400.0 | nM | 197.69 | NCc1csc2ccc(Cl)cc12 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358215 |
|
IC50 | = | 400.0 | nM | 146.14 | O=Cc1ccc2occc2c1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358204 |
|
IC50 | = | 500.0 | nM | 241.11 | O=Cc1csc2ccc(Br)cc12 | Homo sapiens | CHEMBL3390303 | single protein format |
CHEMBL3358195 |
|
IC50 | = | 500.0 | nM | 177.27 | CNCc1cc2ccccc2s1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358199 |
|
Ki | = | 500.0 | nM | 192.29 | CN(C)Cc1cc2cnccc2s1 | Homo sapiens | CHEMBL3390305 | single protein format |
CHEMBL360541 |
|
IC50 | = | 514.0 | nM | 132.17 | NCC#Cc1cccnc1 | Homo sapiens | CHEMBL3705713 | single protein format |
CHEMBL361364 |
|
Ki | = | 520.0 | nM | 173.22 | CCn1cnc(-c2cccnc2)c1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3640762 |
|
Ki | = | 590.0 | nM | 176.24 | Nc1ccc(-c2cccnc2)s1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3358216 |
|
IC50 | = | 600.0 | nM | 143.14 | N#Cc1ccc2occc2c1 | Homo sapiens | CHEMBL3390303 | single protein format |
CHEMBL385008 |
|
IC50 | = | 600.0 | nM | 174.21 | NCc1cc(-c2cccnc2)n[nH]1 | Homo sapiens | CHEMBL3706122 | assay format |
CHEMBL179477 |
|
Ki | = | 620.0 | nM | 145.16 | c1cncc(-n2ccnc2)c1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3358224 |
|
IC50 | = | 680.0 | nM | 159.19 | Cn1ccc2cc(C=O)ccc21 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358196 |
|
IC50 | = | 700.0 | nM | 242.14 | NCc1csc2ccc(Br)cc12 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL178547 |
|
Ki | = | 710.0 | nM | 188.19 | O/N=C/c1ccc(-c2cccnc2)o1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL360999 |
|
IC50 | = | 748.0 | nM | 159.19 | Cn1cnc(-c2cccnc2)c1 | Homo sapiens | CHEMBL3705713 | single protein format |
CHEMBL179398 |
|
Ki | = | 790.0 | nM | 189.24 | O=Cc1ccc(-c2cccnc2)s1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL217125 |
|
IC50 | = | 800.0 | nM | 175.19 | NCc1cc(-c2cccnc2)no1 | Homo sapiens | CHEMBL3706122 | assay format |
CHEMBL3358202 |
|
IC50 | = | 800.0 | nM | 162.21 | O=Cc1cc2ccccc2s1 | Homo sapiens | CHEMBL3390303 | single protein format |
CHEMBL3358201 |
|
Ki | = | 800.0 | nM | 178.26 | CNCc1cc2cccnc2s1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3358196 |
|
Ki | = | 800.0 | nM | 242.14 | NCc1csc2ccc(Br)cc12 | Homo sapiens | CHEMBL3390306 | single protein format |
CHEMBL149808 |
|
Ki | = | 890.0 | nM | 146.19 | CNCC#Cc1cccnc1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3358197 |
|
IC50 | = | 900.0 | nM | 162.21 | O=Cc1ccc2sccc2c1 | Homo sapiens | CHEMBL3390302 | single protein format |
CHEMBL3989843 |
|
IC50 | = | 970.0 | nM | 266.39 | N[C@@H]1C[C@H]1c1ccccc1.N[C@H]1C[C@@H]1c1ccccc1 | Homo sapiens | CHEMBL3705713 | single protein format |
CHEMBL1179 |
|
IC50 | = | 970.0 | nM | 133.19 | N[C@@H]1C[C@H]1c1ccccc1 | Homo sapiens | CHEMBL4422401 | assay format |
CHEMBL179005 |
|
Ki | = | 970.0 | nM | 179.22 | Fc1ccc(-c2ccsc2)cn1 | Homo sapiens | CHEMBL4422431 | cell-based format |
CHEMBL3640760 |
|
IC50 | = | 1000.0 | nM | 175.26 | Cc1cncc(-c2ccsc2)c1 | Homo sapiens | CHEMBL3705713 | single protein format |
CHEMBL3358198 |
|
IC50 | = | 1000.0 | nM | 164.23 | NCc1cc2cnccc2s1 | Homo sapiens | CHEMBL3390302 | single protein format |