P12081 | HARS1_HUMAN | "Histidine--tRNA ligase, cytoplasmic" (HARS1)
3D structures mapped by conservation among orthologs
[ Domain: "Class II aaRS and biotin synthetases" // tRNA-synt_His ]
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[ Domain: "S15/NS1 RNA-binding domain" // WHEP-TRS ]
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[ Domain: "Anticodon-binding domain of Class II aaRS" // HGTP_anticodon ]
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[ Domain: pdbs with more than 2 multi-domains ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL412891 | IC50 | = | 130.0 | nM | 483.47 | Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL694931 | single protein format |