P14550 | AK1A1_HUMAN | Aldo-keto reductase family 1 member A1 (AKR1A1)
3D structures mapped by conservation among orthologs
[ Domain: "TIM barrels" // Aldo_ket_red ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL273910 | IC50 | = | 6.7 | nM | 449.21 | O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1ccc(F)cc12 | Homo sapiens | CHEMBL1174255 | assay format | |
| CHEMBL436 | IC50 | = | 720.0 | nM | 357.35 | COc1ccc2c(C(=S)N(C)CC(=O)O)cccc2c1C(F)(F)F | Homo sapiens | CHEMBL1174255 | assay format |