P15169 | CBPN_HUMAN | Carboxypeptidase N catalytic chain (CPN1)
3D structures mapped by conservation among orthologs
[ Domain: "Prealbumin-like" // CarboxypepD_reg ]
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[ Domain: "Zn-dependent exopeptidases" // Peptidase_M14 ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL236822 | IC50 | = | 2.0 | nM | 205.28 | N=C(N)NCCCC(CS)C(=O)O | Homo sapiens | CHEMBL885910 | single protein format | |
| CHEMBL236822 | Ki | = | 2.0 | nM | 205.28 | N=C(N)NCCCC(CS)C(=O)O | Homo sapiens | CHEMBL901239 | cell-free format | |
| CHEMBL245985 | IC50 | = | 7.0 | nM | 273.75 | N=C(N)Nc1ccc(Cl)c(C(CS)C(=O)O)c1 | Homo sapiens | CHEMBL885910 | single protein format | |
| CHEMBL245787 | IC50 | = | 8.0 | nM | 239.3 | N=C(N)Nc1cccc(C(CS)C(=O)O)c1 | Homo sapiens | CHEMBL885910 | single protein format | |
| CHEMBL245589 | IC50 | = | 58.0 | nM | 231.32 | N=C(N)N1CCCC(C(CS)C(=O)O)C1 | Homo sapiens | CHEMBL885910 | single protein format | |
| CHEMBL246978 | IC50 | = | 60.0 | nM | 189.28 | O=C(O)C(CS)C1CCNCC1 | Homo sapiens | CHEMBL885910 | single protein format | |
| CHEMBL391595 | IC50 | = | 61.0 | nM | 203.31 | O=C(O)C(CS)CC1CCNCC1 | Homo sapiens | CHEMBL885910 | single protein format | |
| CHEMBL246595 | IC50 | = | 357.0 | nM | 197.26 | Nc1cccc(C(CS)C(=O)O)c1 | Homo sapiens | CHEMBL885910 | single protein format | |
| CHEMBL395661 | IC50 | = | 420.0 | nM | 203.31 | O=C(O)C(CS)CC1CCCNC1 | Homo sapiens | CHEMBL885910 | single protein format | |
| CHEMBL394951 | IC50 | = | 1000.0 | nM | 224.28 | N=C(N)c1ccc(C(CS)C(=O)O)cc1 | Homo sapiens | CHEMBL885910 | single protein format |