P16109 | LYAM3_HUMAN | P-selectin (SELP)
3D structures mapped by conservation among orthologs
[ Domain: "C-type lectin-like" // Lectin_C ]
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[ Domain: "EGF/Laminin" // hEGF_2 ]
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[ Domain: pdbs with more than 2 multi-domains ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2312649 | IC50 | = | 400.0 | nM | 520.51 | CN1CCC(NC(=O)c2cnc(Nc3cc(Cl)cc(Cl)c3)nc2NC2CCC(N(C)C)CC2)CC1 | Homo sapiens | CHEMBL2318062 | assay format | |
| CHEMBL2312651 | IC50 | = | 430.0 | nM | 506.44 | CN1CCC(NC(=O)c2cnc(Nc3cc(Cl)cc(Cl)c3)nc2N[C@H]2CCCCNC2=O)CC1 | Homo sapiens | CHEMBL2318062 | assay format | |
| CHEMBL7864 | IC50 | = | 500.0 | nM | 417.68 | CCCCCCCCCCCCC#CC#CCCCCCCCCC(=O)NCCO | Homo sapiens | CHEMBL810718 | cell-based format | |
| CHEMBL375763 | IC50 | = | 570.0 | nM | 461.5 | O=C(O)Cc1ccc(-c2ccc(NC(=O)c3cccc(-c4ccc(O)c(O)c4O)c3)cc2)s1 | Homo sapiens | CHEMBL917095 | single protein format | |
| CHEMBL2311550 | IC50 | = | 580.0 | nM | 467.4 | CC[C@@H](CO)Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1C(=O)NC1CCN(C)CC1 | Homo sapiens | CHEMBL2318062 | assay format | |
| CHEMBL220720 | IC50 | = | 740.0 | nM | 461.5 | O=C(O)Cc1ccc(-c2cccc(NC(=O)c3cccc(-c4ccc(O)c(O)c4O)c3)c2)s1 | Homo sapiens | CHEMBL917095 | single protein format | |
| CHEMBL220254 | IC50 | = | 870.0 | nM | 380.35 | O=C(O)Cc1cccc(-c2ccccc2OC(=O)c2cc(O)c(O)c(O)c2)c1 | Homo sapiens | CHEMBL917095 | single protein format | |
| CHEMBL112485 | IC50 | = | 1000.0 | nM | 312.32 | COc1ccc(CC(=O)O)cc1C1OC(C)C(O)C(O)C1O | Homo sapiens | CHEMBL857691 | single protein format | |
| CHEMBL2312654 | IC50 | = | 1000.0 | nM | 461.4 | Cc1cc(-c2cnc(Nc3cc(Cl)cc(Cl)c3)nc2NC2CCC(N(C)C)CC2)on1 | Homo sapiens | CHEMBL2318062 | assay format |