P19174 | PLCG1_HUMAN | "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1" (PLCG1)
3D structures mapped by conservation among orthologs
[ Domain: "SH2" // SH2 ]
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[ Domain: "SH3" // SH3_1 ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3355737 | IC50 | = | 180.0 | nM | 481.62 | O=S(=O)(c1ccccc1)c1cc(Nc2cc(C3CCCC3)[nH]n2)nc(N[C@H]2CC[C@H](O)CC2)c1 | Homo sapiens | CHEMBL3390067 | cell-based format | |
| CHEMBL3355726 | IC50 | = | 540.0 | nM | 427.53 | Cc1cc(Nc2cc(S(=O)(=O)c3ccccc3)cc(N[C@H]3CC[C@H](O)CC3)n2)n[nH]1 | Homo sapiens | CHEMBL3390067 | cell-based format |