P23471 | PTPRZ_HUMAN | Receptor-type tyrosine-protein phosphatase zeta (PTPRZ1)
3D structures mapped by conservation among orthologs
[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]
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[ Domain: "Carbonic anhydrase" // Carb_anhydrase ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4285054 | IC50 | = | 100.0 | nM | 384.37 | FC(F)(F)Sc1ccc(COc2ccc(SC(F)(F)F)cc2)cc1 | Homo sapiens | CHEMBL4253962 | single protein format | |
| CHEMBL4278170 | IC50 | = | 100.0 | nM | 397.41 | FC(F)(F)Sc1ccc(CNCc2ccc(SC(F)(F)F)cc2)cc1 | Homo sapiens | CHEMBL4253962 | single protein format | |
| CHEMBL4286807 | IC50 | = | 800.0 | nM | 425.42 | O=C(Cc1ccc(SC(F)(F)F)cc1)NCc1ccc(SC(F)(F)F)cc1 | Homo sapiens | CHEMBL4253962 | single protein format |