P27708 | PYR1_HUMAN | CAD protein (CAD)

3D structures mapped by conservation among orthologs

[ Domain: "TIM barrels" // DHOase ]

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[ Domain: "Aspartate/ornithine carbamoyltransferase" // OTCace ]

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[ Domain: "Aspartate/ornithine carbamoyltransferase" // OTCace_N ]

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[ Domain: "Composite domain of metallo-dependent hydrolases" // D-HYD_C ]

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[ Domain: pdbs with more than 2 multi-domains ]

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[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

Ki table

molecule_chembl_id	structure	assay_type	relation	values	units	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL170214		Ki	=	140.0	nM	188.21	O=C1N=C(CS)CC(C(=O)O)N1	Homo sapiens	CHEMBL663682	single protein format
CHEMBL29908		Ki	=	140.0	nM	190.22	O=C1N[C@H](C(=O)O)C[C@H](CS)N1	Homo sapiens	CHEMBL876720	assay format