P32297 | ACHA3_HUMAN | Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3)
3D structures mapped by conservation among orthologs
[ Domain: "Nicotinic receptor ligand binding domain-like" // Neur_chan_LBD ]
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[ Domain: "Neurotransmitter-gated ion-channel transmembrane pore" // Neur_chan_memb ]
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[ Domain: pdbs with more than 2 multi-domains ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL309804 | IC50 | = | 14.0 | nM | 210.67 | N=C1NCCN1Cc1ccc(Cl)nc1 | Homo sapiens | CHEMBL3076135 | cell-based format | |
| CHEMBL365956 | IC50 | = | 15.6 | nM | 269.14 | O=c1c(Br)ccc2n1C[C@@H]1CNC[C@H]2C1 | Homo sapiens | CHEMBL1058165 | cell-based format | |
| CHEMBL3 | IC50 | = | 45.0 | nM | 162.24 | CN1CCC[C@H]1c1cccnc1 | Homo sapiens | CHEMBL3076135 | cell-based format | |
| CHEMBL2270633 | IC50 | = | 180.0 | nM | 268.7 | O=[N+]([O-])/C=C1/NCCCN1Cc1ccc(Cl)nc1 | Homo sapiens | CHEMBL3076135 | cell-based format | |
| CHEMBL3 | Ki | = | 220.0 | nM | 162.24 | CN1CCC[C@H]1c1cccnc1 | Homo sapiens | CHEMBL752378 | cell-based format |