P34897 | GLYM_HUMAN | "Serine hydroxymethyltransferase, mitochondrial" (SHMT2)
3D structures mapped by conservation among orthologs
[ Domain: "C-terminal domain in some PLP-dependent transferases" // SHMT ]
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[ Domain: "PLP-dependent transferases" // Aminotran_5_N ]
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[ Domain: pdbs with more than 2 multi-domains ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4530254 | IC50 | = | 540.0 | nM | 375.25 | COc1ccc(-c2nc3c4nsnc4ccc3n2C)cc1Br | Homo sapiens | CHEMBL4418848 | assay format | |
| CHEMBL582132 | IC50 | = | 690.0 | nM | 357.37 | CCOc1cc(-c2nnc3[nH]c(=O)n(C)c(=O)c3n2)ccc1OC(C)C | Homo sapiens | CHEMBL4418848 | assay format | |
| CHEMBL1528232 | IC50 | = | 710.0 | nM | 268.36 | CCOC(=O)CSc1nc2ccc(N)cc2s1 | Homo sapiens | CHEMBL4418848 | assay format | |
| CHEMBL4555669 | IC50 | = | 850.0 | nM | 375.5 | Cn1nc(C(=O)N2CC=C(c3ccccc3)CC2)c2c1-c1ccsc1CC2 | Homo sapiens | CHEMBL4418848 | assay format |