P35236 | PTN7_HUMAN | Tyrosine-protein phosphatase non-receptor type 7 (PTPN7)
3D structures mapped by conservation among orthologs
[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]
download pymol session
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4750435 | IC50 | = | 130.0 | nM | 488.5 | COc1ccc(-n2cc(-c3ccc4ccc(=O)oc4c3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 | Homo sapiens | CHEMBL4712047 | single protein format | |
| CHEMBL1672291 | Ki | = | 690.0 | nM | 527.0 | CC1=C(C(=O)OC(C)C)C(c2ccc(Cl)cc2)n2c(s/c(=Cc3ccc(OCC(=O)O)cc3)c2=O)=N1 | Homo sapiens | CHEMBL1679238 | assay format | |
| CHEMBL584481 | IC50 | = | 870.0 | nM | 595.7 | O=C1/C(=C/c2cn(-c3ccccc3)nc2-c2ccc(OCc3ccccc3F)cc2)SC(=S)N1CCS(=O)(=O)O | Homo sapiens | CHEMBL1047963 | single protein format | |
| CHEMBL1672291 | IC50 | = | 1000.0 | nM | 527.0 | CC1=C(C(=O)OC(C)C)C(c2ccc(Cl)cc2)n2c(s/c(=Cc3ccc(OCC(=O)O)cc3)c2=O)=N1 | Homo sapiens | CHEMBL1679227 | assay format |