P46934 | NEDD4_HUMAN | E3 ubiquitin-protein ligase NEDD4 (NEDD4)
3D structures mapped by conservation among orthologs
[ Domain: "C2 domain" // C2_1 ]
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[ Domain: "Hect, E3 ligase catalytic domain" // HECT ]
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[ Domain: "WW domain" // WW ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3621955 | IC50 | = | 500.0 | nM | 352.42 | Cc1nc2ccccc2nc1SCC(=O)NC(=O)Nc1ccccc1 | Homo sapiens | CHEMBL3626195 | single protein format | |
| CHEMBL3621954 | IC50 | = | 500.0 | nM | 445.59 | Cc1nn(-c2ccccc2)c(C)c1NC(=O)CN1CCCC(c2nc3ccccc3s2)C1 | Homo sapiens | CHEMBL3626194 | single protein format |