P48163 | MAOX_HUMAN | NADP-dependent malic enzyme (ME1)
3D structures mapped by conservation among orthologs
[ Domain: "NAD(P)-binding Rossmann-fold domains" // Malic_M ]
download pymol session
[ Domain: "Aminoacid dehydrogenase-like, N-terminal domain" // malic ]
download pymol session
[ Domain: "C-terminal domain of Malic enzyme" // Malic_M ]
download pymol session
[ Domain: pdbs with more than 2 multi-domains ]
download pymol session
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL372408 | IC50 | = | 150.0 | nM | 351.41 | O=C1CC(N2CCN(c3ccc(O)cc3)CC2)C(=O)N1c1ccccc1 | Homo sapiens | CHEMBL859587 | single protein format | |
| CHEMBL201911 | IC50 | = | 450.0 | nM | 365.43 | O=C1CC(N2CCN(c3ccc(O)cc3)CC2)C(=O)N1Cc1ccccc1 | Homo sapiens | CHEMBL859587 | single protein format | |
| CHEMBL202332 | IC50 | = | 560.0 | nM | 399.88 | Cc1ccc(N2C(=O)CC(N3CCN(c4ccc(O)cc4)CC3)C2=O)cc1Cl | Homo sapiens | CHEMBL859587 | single protein format |