P49366 | DHYS_HUMAN | Deoxyhypusine synthase (DHPS)
3D structures mapped by conservation among orthologs
[ Domain: "DHS-like NAD/FAD-binding domain" // DS ]
download pymol session
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4555677 | IC50 | = | 62.0 | nM | 371.26 | O=C(Nc1cccc2[nH]ccc12)c1cc2ccc(Br)cc2s1 | Homo sapiens | CHEMBL4358945 | assay format | |
| CHEMBL4543218 | IC50 | = | 92.0 | nM | 418.26 | O=C(Nc1cccc2[nH]ccc12)c1cc2ccc(I)cc2s1 | Homo sapiens | CHEMBL4358945 | assay format | |
| CHEMBL4462702 | IC50 | = | 120.0 | nM | 326.81 | O=C(Nc1cccc2[nH]ccc12)c1cc2ccc(Cl)cc2s1 | Homo sapiens | CHEMBL4358945 | assay format | |
| CHEMBL229457 | IC50 | = | 140.0 | nM | 172.28 | N=C(N)NCCCCCCCN | Homo sapiens | CHEMBL4358945 | assay format | |
| CHEMBL4442298 | IC50 | = | 430.0 | nM | 317.37 | N#Cc1ccc2cc(C(=O)Nc3cccc4[nH]ccc34)sc2c1 | Homo sapiens | CHEMBL4358945 | assay format | |
| CHEMBL4447948 | IC50 | = | 840.0 | nM | 292.38 | CC(C)(C)c1ccc(C(=O)Nc2cccc3[nH]ccc23)cc1 | Homo sapiens | CHEMBL4358945 | assay format |