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P52565 | GDIR1_HUMAN | Rho GDP-dissociation inhibitor 1 (ARHGDIA)

3D structures mapped by conservation among orthologs

[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // Rho_GDI ]

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[ Alpha Fold Model ] (go)


Known binders annotated in ChEMBL

Ki table

molecule_chembl_id structure assay_type relation values units mol_wt smiles organism assay_chembl_id bao_label
CHEMBL3647977 OBDepict OH O CH 3 N N H N N H Ki = 35.0 nM 406.53 Cc1ccc(CN2C3CCC2CC(Nc2ccc4[nH]ncc4c2)C3)cc1OCCO Homo sapiens CHEMBL3705256 single protein format
CHEMBL3647976 OBDepict OH O N N H N N H Ki = 59.0 nM 392.5 OCCOc1cccc(CN2C3CCC2CC(Nc2ccc4[nH]ncc4c2)C3)c1 Homo sapiens CHEMBL3705256 single protein format
CHEMBL3647974 OBDepict H N N N H N Ki = 72.0 nM 332.45 c1ccc(CN2C3CCC2CC(Nc2ccc4[nH]ncc4c2)C3)cc1 Homo sapiens CHEMBL3705256 single protein format
CHEMBL3647975 OBDepict H 3 C N N H N N H Ki = 91.0 nM 346.48 Cc1ccc(CN2C3CCC2CC(Nc2ccc4[nH]ncc4c2)C3)cc1 Homo sapiens CHEMBL3705256 single protein format
CHEMBL3647978 OBDepict N N H N Ki = 806.0 nM 343.47 c1ccc(CN2C3CCC2CC(Nc2cccc4cnccc24)C3)cc1 Homo sapiens CHEMBL3705256 single protein format
CHEMBL3647979 OBDepict H N N N H N Ki = 976.0 nM 318.42 c1ccc(CN2CC3CCC2C3Nc2ccc3[nH]ncc3c2)cc1 Homo sapiens CHEMBL3705256 single protein format