P54098 | DPOG1_HUMAN | DNA polymerase subunit gamma-1 (POLG)

3D structures mapped by conservation among orthologs

[ Domain: "Ribonuclease H-like" // KOG3657 ]

download pymol session

[ Domain: "Adenylyl and guanylyl cyclase catalytic domain-like" // DNA_pol_A_3rd ]

download pymol session

[ Domain: "helical bundle in Bacillus stearothermophilus-like DNA polymerase I" // DNA_pol_A_2nd ]

download pymol session

[ Domain: ""fingers" domain in bacteriophage RB69-like DNA polymerase I" // DNA_pol_A_1st ]

download pymol session

[ Domain: pdbs with more than 2 multi-domains ]

download pymol session

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

IC50 table

molecule_chembl_id	structure	assay_type	relation	values	units	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL483492		IC50	=	500.0	nM	483.18	Cc1cn([C@@H]2C[C@@H](F)[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)nc1N	Homo sapiens	CHEMBL658102	single protein format