P67775 | PP2AA_HUMAN | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA)
3D structures mapped by conservation among orthologs
[ Domain: "Metallo-dependent phosphatases" // Metallophos_2_1 ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4750435 | IC50 | = | 200.0 | nM | 488.5 | COc1ccc(-n2cc(-c3ccc4ccc(=O)oc4c3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 | Homo sapiens | CHEMBL4712042 | single protein format | |
| CHEMBL2368224 | IC50 | = | 304.0 | nM | 594.7 | C=C1[C@@H](CO)O[C@@H]2CC[C@@]3(CC[C@H](/C=C/[C@@H](C)[C@@H]4CC(C)=C[C@@]5(O[C@H](C[C@@](C)(O)C(=O)O)CC[C@H]5O)O4)O3)O[C@H]2[C@@H]1O | Homo sapiens | CHEMBL768151 | single protein format |