P78356 | PI42B_HUMAN | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (PIP4K2B)
3D structures mapped by conservation among orthologs
[ Domain: "SAICAR synthase" // PIP5K ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4855730 | IC50 | = | -47100.0 | nM | 452.51 | Nc1ncc(-c2ccc(NS(=O)(=O)C3CC3)cc2F)cc1-c1ccc2c(c1)CCNC2=O | Homo sapiens | CHEMBL4804757 | cell-based format | |
| CHEMBL4867931 | IC50 | = | -31500.0 | nM | 464.55 | COc1cc(NS(=O)(=O)C2CC2)ccc1-c1cnc(N)c(-c2ccc3c(c2)CCNC3=O)c1 | Homo sapiens | CHEMBL4804757 | cell-based format | |
| CHEMBL4868141 | IC50 | = | -8900.0 | nM | 532.67 | Nc1ncc(-c2ccc(NS(=O)(=O)C3CC3)cc2OC2CCCCC2)cc1-c1ccc2c(c1)CCNC2=O | Homo sapiens | CHEMBL4804757 | cell-based format |