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Q01650 | LAT1_HUMAN | Large neutral amino acids transporter small subunit 1 (SLC7A5)

3D structures mapped by conservation among orthologs

[ Domain: "Sodium:neurotransmitter symporter family (SNF)-like" // AA_permease_2_1 ]

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[ Alpha Fold Model ] (go)


Known binders annotated in ChEMBL

IC50 table

molecule_chembl_id structure assay_type relation values units mol_wt smiles organism assay_chembl_id bao_label
CHEMBL4538666 OBDepict HO O NH 2 H Cl Cl O O NH 2 N IC50 = 790.0 nM 472.33 Nc1cc(COc2c(Cl)cc(C[C@H](N)C(=O)O)cc2Cl)c2oc(-c3ccccc3)nc2c1 Homo sapiens CHEMBL4425979 cell-based format
CHEMBL4526588 OBDepict Cl N S S N N O F F F IC50 = 980.0 nM 313.71 FC(F)(F)Oc1ccc(/N=c2ssnc2Cl)nc1 Homo sapiens CHEMBL4407759 single protein format