Q04721 | NOTC2_HUMAN | Neurogenic locus notch homolog protein 2 (NOTCH2)
3D structures mapped by conservation among orthologs
[ Domain: "Notch heterodimerization domain" // NOD ]
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[ Domain: "EGF/Laminin" // hEGF_2 ]
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[ Domain: "Lin12/Notch repeat" // Notch ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3410161 | IC50 | = | 1.0 | nM | 536.55 | CN1C(=O)[C@@H](NC(=O)[C@H](CCC(F)(F)F)[C@@H](C(N)=O)c2ccccc2)N=C(c2ccccc2)c2ccccc21 | Homo sapiens | CHEMBL3412055 | cell-based format |