Q13332 | PTPRS_HUMAN | Receptor-type tyrosine-protein phosphatase S (PTPRS)

3D structures mapped by conservation among orthologs

[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set ]

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[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_2 ]

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[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // fn3 ]

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[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]

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[ Domain: pdbs with more than 2 multi-domains ]

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[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

IC50 table

molecule_chembl_id	structure	assay_type	relation	values	units	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL1438439		IC50	=	500.0	nM	318.24	O=c1c(-c2cc(O)c(O)c(O)c2)coc2cc(O)c(O)c(O)c12	Homo sapiens	CHEMBL3744704	single protein format
CHEMBL55415		IC50	=	600.0	nM	286.24	O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12	Homo sapiens	CHEMBL3744704	single protein format
CHEMBL3739950		IC50	=	800.0	nM	260.2	O=c1cc(-c2ccco2)oc2cc(O)c(O)c(O)c12	Homo sapiens	CHEMBL3744704	single protein format
CHEMBL3740878		IC50	=	900.0	nM	260.2	O=c1cc(-c2ccoc2)oc2cc(O)c(O)c(O)c12	Homo sapiens	CHEMBL3744704	single protein format