Q13555 | KCC2G_HUMAN | Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G)
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
download pymol session
[ Domain: "NTF2-like" // DUF4440 ]
download pymol session
[ Domain: pdbs with more than 2 multi-domains ]
download pymol session
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4859660 | IC50 | = | -23000.0 | nM | 378.36 | Nc1ncc(-c2cccc([N+](=O)[O-])c2F)cc1-c1ccc2c(c1)CCNC2=O | Homo sapiens | CHEMBL4804354 | cell-based format | |
| CHEMBL4855542 | IC50 | = | -13600.0 | nM | 372.45 | Nc1ncc(-c2cccc3ncsc23)cc1-c1ccc2c(c1)CCNC2=O | Homo sapiens | CHEMBL4804354 | cell-based format | |
| CHEMBL4860979 | IC50 | = | -13000.0 | nM | 466.54 | CN(C1CC1)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc4c(c3)CCNC4=O)c2)c(F)c1 | Homo sapiens | CHEMBL4804354 | cell-based format | |
| CHEMBL4868141 | IC50 | = | -12000.0 | nM | 532.67 | Nc1ncc(-c2ccc(NS(=O)(=O)C3CC3)cc2OC2CCCCC2)cc1-c1ccc2c(c1)CCNC2=O | Homo sapiens | CHEMBL4804354 | cell-based format | |
| CHEMBL4855730 | IC50 | = | -6400.0 | nM | 452.51 | Nc1ncc(-c2ccc(NS(=O)(=O)C3CC3)cc2F)cc1-c1ccc2c(c1)CCNC2=O | Homo sapiens | CHEMBL4804354 | cell-based format | |
| CHEMBL388978 | IC50 | = | 0.387 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328336 | single protein format | |
| CHEMBL3975634 | IC50 | = | 0.7 | nM | 452.51 | CN[C@H]1CC2OC([C@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(O)=NC4 | Homo sapiens | CHEMBL3707764 | single protein format | |
| CHEMBL288441 | IC50 | = | 184.0 | nM | 530.46 | COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl | Homo sapiens | CHEMBL1244345 | single protein format |