Q15109 | RAGE_HUMAN | Advanced glycosylation end product-specific receptor (AGER)
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_4 ]
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[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_15 ]
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[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // UNK_F_TYPE ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4075936 | Ki | = | 25.0 | nM | 327.86 | O=C(c1ccc(Cl)cc1)N(Cc1ccccc1)C1CCCCC1 | Homo sapiens | CHEMBL4030328 | cell-based format | |
| CHEMBL2205559 | IC50 | = | 660.0 | nM | 561.19 | CCCCc1sc(-c2ccc(OCC3CCCN(CC)C3)cc2)nc1-c1ccc(Oc2ccc(Cl)cc2)cc1 | Homo sapiens | CHEMBL2210069 | single protein format | |
| CHEMBL2205572 | IC50 | = | 910.0 | nM | 533.14 | CCCCc1sc(-c2ccc(OCCN3CCCC3)cc2)nc1-c1ccc(Oc2ccc(Cl)cc2)cc1 | Homo sapiens | CHEMBL2210069 | single protein format |