Q15831 | STK11_HUMAN | Serine/threonine-protein kinase STK11 (STK11)
3D structures mapped by conservation among orthologs
[ Domain: "ARM repeat" // 14-3-3 ]
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[ Domain: "Protein kinase" // Pkinase_Tyr ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4860979 | IC50 | = | -600.0 | nM | 466.54 | CN(C1CC1)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc4c(c3)CCNC4=O)c2)c(F)c1 | Homo sapiens | CHEMBL4804408 | cell-based format | |
| CHEMBL388978 | IC50 | = | 70.9 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328474 | single protein format |