Q2NL67 | PARP6_HUMAN | Protein mono-ADP-ribosyltransferase PARP6 (PARP6)
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3740897 | IC50 | = | 83.0 | nM | 500.46 | C[C@H]1Cn2c(nnc2C(C)(F)F)CN1C(=O)c1cccc(C(F)(F)c2n[nH]c(=O)c3ccccc23)c1 | Homo sapiens | CHEMBL3743853 | cell-based format | |
| CHEMBL3740104 | IC50 | = | 640.0 | nM | 450.5 | N#Cc1cccnc1N1CCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4ccccc34)c2)CC1 | Homo sapiens | CHEMBL3743853 | cell-based format |