Q8N5S9 | KKCC1_HUMAN | Calcium/calmodulin-dependent protein kinase kinase 1 (CAMKK1)
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4870467 | IC50 | = | 27.0 | nM | 383.45 | O=C(O)c1ccc(-c2ccnc3[nH]c(-c4ccccc4)nc23)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format | |
| CHEMBL4857253 | IC50 | = | 31.0 | nM | 359.43 | O=C(O)c1ccc(-c2ccnc(Nc3ccccc3)n2)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format | |
| CHEMBL558642 | IC50 | = | 33.0 | nM | 382.46 | O=C(O)c1ccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format | |
| CHEMBL388978 | IC50 | = | 42.0 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328338 | single protein format | |
| CHEMBL265470 | IC50 | = | 120.0 | nM | 374.35 | CC(=O)O.O=C(O)c1ccc2c3c1cccc3c(=O)n1c3ccccc3nc21 | Homo sapiens | CHEMBL1051323 | single protein format | |
| CHEMBL4125686 | IC50 | = | 195.0 | nM | 306.37 | O=C(O)c1ccc(-c2c[nH]c3ncccc23)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format | |
| CHEMBL4877552 | IC50 | = | 238.0 | nM | 383.45 | O=C(O)c1ccc(-c2cnn3ccc(-c4ccccc4)nc23)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format | |
| CHEMBL4852523 | IC50 | = | 239.0 | nM | 317.39 | O=C(O)c1ccc(-c2ccnc3ccccc23)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format | |
| CHEMBL4875005 | IC50 | = | 384.0 | nM | 399.52 | O=C(O)c1ccc(-c2csc3ncc(-c4ccccc4)cc23)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format | |
| CHEMBL4862562 | IC50 | = | 407.0 | nM | 324.4 | O=C(O)c1ccc(-c2ncnc3ccsc23)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format | |
| CHEMBL4866741 | IC50 | = | 961.0 | nM | 383.45 | O=C(O)c1ccc(-c2coc3ncc(-c4ccccc4)cc23)cc1C1CCCC1 | Homo sapiens | CHEMBL4827617 | single protein format |