Q8NB16 | MLKL_HUMAN | Mixed lineage kinase domain-like protein (MLKL)
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
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[ Domain: "Mixed lineage kinase domain-like (MLKL) N-terminal domain" // RPW8_like ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4868141 | IC50 | = | 200.0 | nM | 532.67 | Nc1ncc(-c2ccc(NS(=O)(=O)C3CC3)cc2OC2CCCCC2)cc1-c1ccc2c(c1)CCNC2=O | Homo sapiens | CHEMBL4804432 | cell-based format |