Q96LB2 | MRGX1_HUMAN | Mas-related G-protein coupled receptor member X1 (MRGPRX1)
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3730717 | IC50 | = | 182.0 | nM | 425.57 | COc1ccccc1C(O)/C=C1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 | Homo sapiens | CHEMBL3734551 | single protein format | |
| CHEMBL3730599 | IC50 | = | 607.0 | nM | 446.98 | O=C(Nc1ccccc1Cl)O[C@@H]1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 | Homo sapiens | CHEMBL3734551 | single protein format | |
| CHEMBL3727861 | IC50 | = | 630.0 | nM | 413.54 | OC(/C=C1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1)c1ccc(F)cc1 | Homo sapiens | CHEMBL3734551 | single protein format | |
| CHEMBL3343995 | IC50 | = | 800.0 | nM | 423.56 | COc1ccccc1C(=O)/C=C1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 | Homo sapiens | CHEMBL3388388 | cell-based format |