Q9NXA8 | SIR5_HUMAN | "NAD-dependent protein deacylase sirtuin-5, mitochondrial" (SIRT5)
3D structures mapped by conservation among orthologs
[ Domain: "DHS-like NAD/FAD-binding domain" // SIR2_1st ]
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[ Domain: "Rubredoxin-related" // SIR2_2nd_4 ]
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[ Domain: pdbs with more than 2 multi-domains ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL46469 | IC50 | = | 100.0 | nM | 226.23 | O=C1c2c(O)cccc2Cc2cccc(O)c21 | Homo sapiens | CHEMBL4037960 | single protein format | |
| CHEMBL4286528 | IC50 | = | 450.0 | nM | 558.73 | O=C(O)CCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CCSc2ccccc21 | Homo sapiens | CHEMBL4256974 | single protein format | |
| CHEMBL4290465 | IC50 | = | 890.0 | nM | 502.59 | O=C(O)CCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc(O)c1 | Homo sapiens | CHEMBL4256974 | single protein format |