Q9P0U3 | SENP1_HUMAN | Sentrin-specific protease 1 (SENP1)
3D structures mapped by conservation among orthologs
[ Domain: "Cysteine proteinases" // Peptidase_C48 ]
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[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4780770 | IC50 | = | 760.0 | nM | 541.7 | CCNc1ccc2sc(C(=O)NCc3cccc(NC(=O)c4cccs4)c3)c(OCc3ccccc3)c2c1 | Homo sapiens | CHEMBL4772833 | cell-based format | |
| CHEMBL4791433 | IC50 | = | 790.0 | nM | 541.7 | CN(C)c1ccc2sc(C(=O)NCc3cccc(NC(=O)c4cccs4)c3)c(OCc3ccccc3)c2c1 | Homo sapiens | CHEMBL4772833 | cell-based format | |
| CHEMBL2012938 | Ki | = | 930.0 | nM | 562.57 | O=C(Cc1ccccc1)Oc1c(OC(=O)Cc2ccccc2)c(-c2ccc(O)cc2)c(O)c(O)c1-c1ccc(O)cc1 | Homo sapiens | CHEMBL4479673 | assay format | |
| CHEMBL4792569 | IC50 | = | 1000.0 | nM | 527.67 | CNc1ccc2sc(C(=O)NCc3cccc(NC(=O)c4cccs4)c3)c(OCc3ccccc3)c2c1 | Homo sapiens | CHEMBL4772833 | cell-based format |