Q9UBM7 | DHCR7_HUMAN | 7-dehydrocholesterol reductase (DHCR7)
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2172347 | IC50 | = | 2.3 | nM | 317.82 | COc1cc2c(cc1O)CCN(CCc1ccc(Cl)cc1)C2 | Homo sapiens | CHEMBL2175827 | cell-based format | |
| CHEMBL2172349 | IC50 | = | 120.0 | nM | 313.4 | COc1cccc(CCN2CCc3cc(O)c(OC)cc3C2)c1 | Homo sapiens | CHEMBL2175827 | cell-based format | |
| CHEMBL2172263 | IC50 | = | 500.0 | nM | 482.99 | O=C(O)c1ccc(CCN2CCN(C/C=C/c3ccc(Cl)cc3)CC2)cc1.O=S(=O)(O)O | Homo sapiens | CHEMBL2175827 | cell-based format |