Q9UGI6 | KCNN3_HUMAN | Small conductance calcium-activated potassium channel protein 3 (KCNN3)
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
Ki table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3040285 | IC50 | = | 31.0 | nM | 460.63 | c1cc2cc(c1)CNc1cc[n+](c3ccccc13)CCCCC[n+]1ccc(c3ccccc31)NC2 | Homo sapiens | CHEMBL2394433 | single protein format | |
| CHEMBL476339 | IC50 | = | 59.0 | nM | 268.35 | Cc1ccnc(Nc2nc(-c3ccccn3)cs2)c1 | Homo sapiens | CHEMBL986170 | cell-based format | |
| CHEMBL360621 | IC50 | = | 60.0 | nM | 460.63 | c1ccc2c(c1)c1cc[n+]2CCCCC[n+]2ccc(c3ccccc32)NCc2ccc(cc2)CN1 | Homo sapiens | CHEMBL2394433 | single protein format | |
| CHEMBL472452 | IC50 | = | 350.0 | nM | 264.74 | Clc1cc(NCc2cccs2)n2nccc2n1 | Homo sapiens | CHEMBL995892 | cell-based format | |
| CHEMBL489770 | IC50 | = | 543.0 | nM | 254.32 | c1ccc(Nc2nc(-c3ccccn3)cs2)nc1 | Homo sapiens | CHEMBL986170 | cell-based format | |
| CHEMBL469732 | IC50 | = | 1000.0 | nM | 272.74 | C[C@@H](Nc1cc(Cl)nc2ccnn12)c1ccccc1 | Homo sapiens | CHEMBL995892 | cell-based format |