Q9UKK3 | PARP4_HUMAN | Protein mono-ADP-ribosyltransferase PARP4 (PARP4)
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3764816 | IC50 | = | 254.0 | nM | 380.36 | Cn1ncnc1[C@@H]1c2n[nH]c(=O)c3cc(F)cc(c23)N[C@H]1c1ccc(F)cc1 | Homo sapiens | CHEMBL3995363 | assay format | |
| CHEMBL1094636 | IC50 | = | 330.0 | nM | 320.4 | NC(=O)c1cccc2cn(-c3ccc([C@@H]4CCCNC4)cc3)nc12 | Homo sapiens | CHEMBL1116321 | single protein format | |
| CHEMBL521686 | IC50 | = | 410.0 | nM | 434.47 | O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCN(C(=O)C2CC2)CC1 | Homo sapiens | CHEMBL3995363 | assay format | |
| CHEMBL595018 | IC50 | = | 440.0 | nM | 307.35 | O=C1NCC2c3c(cccc31)CCN2C(=O)Cc1cccnc1 | Homo sapiens | CHEMBL1074656 | single protein format | |
| CHEMBL609002 | IC50 | = | 660.0 | nM | 322.37 | O=C1NCC2c3c(cccc31)CCN2C(=O)CCc1cnccn1 | Homo sapiens | CHEMBL1074656 | single protein format | |
| CHEMBL1173055 | IC50 | = | 839.0 | nM | 323.37 | CNCc1ccc(-c2[nH]c3cc(F)cc4c3c2CCNC4=O)cc1 | Homo sapiens | CHEMBL3995363 | assay format |