Q9UM07 | PADI4_HUMAN | Protein-arginine deiminase type-4 (PADI4)

3D structures mapped by conservation among orthologs

[ Domain: "Common fold of diphtheria toxin/transcription factors/cytochrome f" // PAD_M ]

download pymol session

[ Domain: "Pentein" // PAD,PAD_M ]

download pymol session

[ Domain: "Pentein" // PAD ]

download pymol session

[ Domain: "Cupredoxin-related" // PAD_N ]

download pymol session

[ Domain: pdbs with more than 2 multi-domains ]

download pymol session

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

IC50 table

molecule_chembl_id	structure	assay_type	relation	values	units	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL4539512		IC50	=	50.0	nM	473.58	COc1cc(C(=O)N2CC[C@@H](O)[C@@H](N)C2)cc2nc(-c3cc4ccccc4n3CC3CC3)n(C)c12	Homo sapiens	CHEMBL4425347	single protein format
CHEMBL58150		IC50	=	240.0	nM	295.25	NC1=CC(=O)c2ccc(-c3cccc(C(=O)O)n3)nc2C1=O	Homo sapiens	CHEMBL3119092	single protein format
CHEMBL1910970		IC50	=	400.0	nM	452.36	N=C(CF)NCCC[C@H](NC(=O)c1ccccc1C(=O)O)C(N)=O.O=C(O)C(F)(F)F	Homo sapiens	CHEMBL1914114	assay format
CHEMBL3113470		IC50	=	560.0	nM	253.06	NC1=C(Br)C(=O)c2cccnc2C1=O	Homo sapiens	CHEMBL3119092	single protein format
CHEMBL57818		IC50	=	640.0	nM	251.25	NC1=CC(=O)c2ccc(-c3ccccn3)nc2C1=O	Homo sapiens	CHEMBL3119092	single protein format
CHEMBL60908		IC50	=	1000.0	nM	174.16	NC1=CC(=O)c2cccnc2C1=O	Homo sapiens	CHEMBL3119092	single protein format