Q9Y6R4 | M3K4_HUMAN | Mitogen-activated protein kinase kinase kinase 4 (MAP3K4)
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
IC50 table
| molecule_chembl_id | structure | assay_type | relation | values | units | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4859660 | IC50 | = | -9600.0 | nM | 378.36 | Nc1ncc(-c2cccc([N+](=O)[O-])c2F)cc1-c1ccc2c(c1)CCNC2=O | Homo sapiens | CHEMBL4804421 | cell-based format | |
| CHEMBL4860979 | IC50 | = | -8800.0 | nM | 466.54 | CN(C1CC1)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc4c(c3)CCNC4=O)c2)c(F)c1 | Homo sapiens | CHEMBL4804421 | cell-based format |